Leitat is pleased to announce the development of a novel enzyme screening platform that represents a significant advancement over commercially available multiwell plates, such as those produced by NUNC®, COSTAR®, and CORNING®.
This newly designed bioreactor introduces several key improvements:
- It requires less reagent volume while using the same type of enzyme, leading to more cost-efficient and environmentally sustainable testing.
- The bioreactor is designed for multiple uses, capable of being reused for over ten cycles. This is achievable by implementing a simple washing procedure with phosphate-buffered saline (PBS) after each test.
- Furthermore, the platform’s reusability is extended through a regeneration process: after immersion in a 70% ethanol solution for one hour, the adhesive can be removed and easily replaced, allowing for continued operation without the need for a full device replacement.
The platform has been successfully validated with oxidoreductase enzymes developed by the University of Groningen (RUG) as part of the project, specifically alditol oxidase and eugenol oxidase.
In recognition of its innovative design and potential impact, the technology has been submitted for European patent protection and is currently under review (Application No. EP24383458.7).
This development underscores Leitat’s ongoing commitment to advancing sustainable, efficient solutions for biotechnology and industrial research.